Elephantiasis nostras verrucosa: a review

Am J Clin Dermatol. 2008;9(3):141-6. doi: 10.2165/00128071-200809030-00001.


Elephantiasis nostras verrucosa (ENV) is a rare and dramatic sequela of chronic nonfilarial lymphedema. The condition is characterized by papules, verrucous lesions, enlargement, and woody fibrosis of the affected area. ENV is a progressive condition, and, without intervention, ongoing deformity and disability will result. Management of ENV is often challenging, but a variety of successful medical and surgical treatment strategies have been reported.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Disease Progression
  • Elephantiasis* / diagnosis
  • Elephantiasis* / therapy
  • Humans
  • Leg Dermatoses / diagnosis
  • Leg Dermatoses / therapy
  • Prognosis