[Fluorine, an essential element for medicinal chemistry]

D Bonnet-Delpon

doi:10.1016/j.pharma.2007.12.001

[Fluorine, an essential element for medicinal chemistry]

Ann Pharm Fr. 2008 Jan;66(1):56-9. doi: 10.1016/j.pharma.2007.12.001. Epub 2008 Apr 2.

[Article in French]

Author

D Bonnet-Delpon¹

Affiliation

¹ UMR-8076-CNRS, molécules fluorées, laboratoire BioCIS, faculte de Pharmacie, universite Paris-Sud, rue J.-B.-Clément, 92296 Châtenay-Malabry, France. daniele.bonnet-delpon@cep.u-psud.fr

PMID: 18435988
DOI: 10.1016/j.pharma.2007.12.001

Abstract

Because of the intrinsic properties of the fluorine atom, organic fluoride compounds have unique properties of particular importance in the pharmaceutical industry. The effect of fluorine is illustrated by selected examples of medicinal chemistry.

Publication types

English Abstract

MeSH terms

Chemistry, Pharmaceutical*
Drug Industry
Fluorine / chemistry*
Fluorine Compounds / chemistry
Fluorine Compounds / pharmacology
Fluorine Compounds / therapeutic use
Proteins / chemistry

Substances

Fluorine Compounds
Proteins
Fluorine