Fire in the hole: pore dilation of the capsaicin receptor TRPV1

Nat Neurosci. 2008 May;11(5):528-9. doi: 10.1038/nn0508-528.
No abstract available

Publication types

  • Comment
  • News

MeSH terms

  • Animals
  • Capsaicin / pharmacology
  • Cell Membrane Permeability / drug effects
  • Cell Membrane Permeability / genetics
  • Humans
  • Hyperalgesia / genetics
  • Hyperalgesia / metabolism*
  • Inflammation Mediators / pharmacology
  • Ion Channel Gating / drug effects
  • Ion Channel Gating / physiology*
  • Ions / metabolism
  • Models, Molecular
  • Neurogenic Inflammation / chemically induced
  • Neurogenic Inflammation / metabolism
  • Neurogenic Inflammation / physiopathology
  • Nociceptors / drug effects
  • Nociceptors / metabolism*
  • Pain / genetics
  • Pain / metabolism*
  • Pain / physiopathology
  • Sensory Receptor Cells / drug effects
  • Sensory Receptor Cells / metabolism*
  • Sensory System Agents / pharmacology
  • Signal Transduction / drug effects
  • Signal Transduction / physiology
  • TRPV Cation Channels / drug effects
  • TRPV Cation Channels / genetics
  • TRPV Cation Channels / metabolism*

Substances

  • Inflammation Mediators
  • Ions
  • Sensory System Agents
  • TRPV Cation Channels
  • TRPV1 protein, mouse
  • Capsaicin