[Morphological magnetic resonance imaging: its value for the diagnosis of neurodegenerative diseases]

Dtsch Med Wochenschr. 2008 May;133 Suppl 1:S15-8. doi: 10.1055/s-2008-1075681.
[Article in German]


Magnetic resonance imaging (MRI) plays an important role in differentiating idiopathic Parkinson's disease (PD) from its atypical forms. Causes like chronic vascular disease and normal-pressure hydrocephalus are easily visualized. Furthermore, specific atrophy patterns can be found with multi-system atrophies, corticobasal degeneration and progressive supranuclear palsy. In addition the review also deals with specific imaging criteria of other neurodegenerative disorders, such as Wilson's disease, neurodegeneration with iron accumulation in the brain and Huntington's chorea. MRI is of minor importance for differentiating Alzheimer's disease from frontotemporal dementia or dementia with Lewy bodies. However, specific patterns are found in cerebral amyloid angiopathy and prion diseases..

Publication types

  • English Abstract
  • Review

MeSH terms

  • Basal Ganglia / blood supply
  • Basal Ganglia / pathology
  • Brain Infarction / pathology
  • Brain Neoplasms / pathology
  • Brain Neoplasms / secondary
  • Cerebellum / pathology
  • Corpus Striatum / pathology
  • Dementia / pathology
  • Diagnosis, Differential
  • Dystonic Disorders / pathology
  • Hepatolenticular Degeneration / pathology
  • Humans
  • Huntington Disease / pathology
  • Hydrocephalus, Normal Pressure / pathology
  • Magnetic Resonance Imaging*
  • Neurodegenerative Diseases / diagnosis*
  • Neurodegenerative Diseases / pathology
  • Parkinson Disease / diagnosis
  • Parkinson Disease / pathology
  • Shy-Drager Syndrome / pathology
  • Substantia Nigra / pathology
  • Supranuclear Palsy, Progressive / pathology