Abstract
The study analyzed the changes in the shape of the flow-volume curve after fenoterol (Berotec) inhalation in school age healthy children. Significant increase of FEF25-75%, FEF50%, FEF25% values were seen. The authors demonstrated that bronchodilatation was not related to sex, height, weight and children's age, but it's value is indirectly proportional to the at-rest state of the airways. It seems, basing on results of this study, that FEV1 and FEF25-75% are the best indexes of dilatation tests. Increases of 10% and 30% are significant of bronchodilatation.
MeSH terms
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Adolescent
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Bronchi / drug effects
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Bronchi / physiology*
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Bronchodilator Agents
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Child
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Female
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Fenoterol / pharmacology
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Forced Expiratory Volume / drug effects
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Forced Expiratory Volume / physiology
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Humans
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Male
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Maximal Expiratory Flow Rate / drug effects
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Maximal Expiratory Flow Rate / physiology
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Maximal Expiratory Flow-Volume Curves / drug effects
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Maximal Expiratory Flow-Volume Curves / physiology
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Maximal Midexpiratory Flow Rate / drug effects
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Maximal Midexpiratory Flow Rate / physiology
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Models, Biological*
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Pulmonary Ventilation / drug effects
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Pulmonary Ventilation / physiology*
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Reference Standards
Substances
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Bronchodilator Agents
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Fenoterol