KRAS mutation signature in colorectal tumors significantly overlaps with the cetuximab response signature

MeSH terms

• Antibodies, Monoclonal / pharmacology
• Antibodies, Monoclonal / therapeutic use*
• Antibodies, Monoclonal, Humanized
• Antineoplastic Agents / pharmacology
• Antineoplastic Agents / therapeutic use*
• Cetuximab
• Cluster Analysis
• Colorectal Neoplasms / drug therapy*
• Colorectal Neoplasms / genetics
• Colorectal Neoplasms / metabolism
• Colorectal Neoplasms / pathology
• ErbB Receptors / antagonists & inhibitors*
• ErbB Receptors / metabolism
• Gene Expression Profiling / methods
• Gene Expression Regulation, Neoplastic*
• Humans
• Mutation*
• Neoplasm Staging
• Oligonucleotide Array Sequence Analysis
• Patient Selection*
• Proto-Oncogene Proteins / genetics*
• Proto-Oncogene Proteins p21(ras)
• Treatment Outcome
• ras Proteins / genetics*