MassNet: a functional annotation service for protein mass spectrometry data

Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W491-5. doi: 10.1093/nar/gkn241. Epub 2008 Apr 29.


Although mass spectrometry has been frequently used to identify proteins, there are no web servers that provide comprehensive functional annotation of those identified proteins. It is necessary to provide such web service due to a rapid increase in the data. We, therefore, introduce MassNet, which provides (i) physico-chemical analysis information, (ii) KEGG pathway assignment (iii) Gene Ontology mapping and (iv) protein-protein interaction (PPI) prediction for the data from MASCOT, Prospector and Profound. MassNet provides the prediction information for PPIs using both 3D structural interaction and experimental interaction deposited in PSIMAP, BIND, DIP, HPRD, IntAct, MINT, CYGD and BioGrid. The web service is freely available at or

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Protein
  • Internet
  • Mass Spectrometry*
  • Protein Interaction Mapping
  • Proteins / chemistry*
  • Proteins / genetics
  • Proteins / metabolism*
  • Software*
  • User-Computer Interface


  • Proteins