Cost-effectiveness of a disease management programme for secondary prevention of coronary heart disease and heart failure in primary care

Heart. 2008 Dec;94(12):1601-6. doi: 10.1136/hrt.2007.125708. Epub 2008 May 1.


Objective: To determine if a disease management programme for patients with coronary heart disease and heart failure represents an efficient use of health services resources.

Methods: We carried out an economic evaluation alongside a cluster randomised control trial of 1163 patients with coronary heart disease and chronic heart failure in 20 primary care practices in the United Kingdom. Practices were randomised to either a control group, where patients received standard general practice care, or an intervention group where patients had access to a specialist nurse-led disease management programme. We estimated costs in both groups for coronary heart disease-related resource use. The main outcome measure used in the economic evaluation was quality adjusted life years (QALY) measured using the EuroQol.

Results: The disease management programme was associated with an increase in the QALY measured of 0.03 per year and an increase in the total NHS costs of 425 pounds (540 euros), of this only 83 pounds was directly associated with the provision of the nurse clinics. The clinics generated additional QALY at an incremental cost of 13 pounds 158 per QALY compared to the control group.

Conclusions: The use of a nurse-led disease management programme is associated with increased costs in other coronary heart disease-related services as well as for the costs of the clinics. They are also associated with improvements in health. Even in the short term these disease management programmes may represent a cost-effective service, as additional QALY are generated at an acceptable extra cost.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Chronic Disease
  • Cluster Analysis
  • Coronary Disease / economics
  • Coronary Disease / nursing
  • Coronary Disease / prevention & control*
  • Cost-Benefit Analysis
  • Disease Management
  • Drug Costs
  • Family Practice / economics
  • Family Practice / statistics & numerical data
  • Female
  • Health Resources / economics
  • Health Resources / statistics & numerical data
  • Heart Failure / economics
  • Heart Failure / nursing
  • Heart Failure / prevention & control*
  • Humans
  • Male
  • Nurse Clinicians / economics
  • Nurse Clinicians / statistics & numerical data
  • Quality of Life
  • Quality-Adjusted Life Years
  • Secondary Prevention