Cost-effectiveness of lung volume reduction surgery

Proc Am Thorac Soc. 2008 May 1;5(4):406-11. doi: 10.1513/pats.200707-095ET.


Lung volume reduction surgery (LVRS) is a costly procedure that can improve quality and quantity of life. Given the prevalence of emphysema, the costs involved with its management, and resource constraints on all health care delivery systems, evaluating the cost-effectiveness of LVRS is important. In this article, we describe the purposes and principles of cost-effectiveness analysis and how those principles were applied in evaluating LVRS. We present the results of the cost-effectiveness analysis that was conducted alongside the National Emphysema Treatment Trial and other economic studies of LVRS and discuss how these should be interpreted in the context of current reimbursement guidelines.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cost-Benefit Analysis
  • Humans
  • Multicenter Studies as Topic
  • Outcome and Process Assessment, Health Care
  • Pneumonectomy / economics*
  • Pulmonary Emphysema / surgery*
  • Quality-Adjusted Life Years
  • Randomized Controlled Trials as Topic
  • United States