DAnTE: a statistical tool for quantitative analysis of -omics data

Bioinformatics. 2008 Jul 1;24(13):1556-8. doi: 10.1093/bioinformatics/btn217. Epub 2008 May 3.


Data Analysis Tool Extension (DAnTE) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects. The graphical user interface (GUI) is designed to be very intuitive and user friendly.

Availability: DAnTE may be downloaded free of charge at http://omics.pnl.gov/software/.

Supplementary information: An example dataset with instructions on how to perform a series of analysis steps is available at http://omics.pnl.gov/software/

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms*
  • Data Interpretation, Statistical*
  • Databases, Protein*
  • Peptide Mapping / methods*
  • Proteome / chemistry*
  • Proteomics / methods*
  • Software*


  • Proteome