Energetics of protein translocation into mitochondria

Biochim Biophys Acta. Jul-Aug 2008;1777(7-8):758-62. doi: 10.1016/j.bbabio.2008.04.009. Epub 2008 Apr 12.

Abstract

Biogenesis of mitochondria depends on the coordinated action of at least six protein translocases present in both mitochondrial membranes. They use different energy sources to drive unidirectional transport of proteins across and into mitochondrial membranes. Here we present an overview on the energetic requirements of different mitochondrial import pathways.

Publication types

  • Review

MeSH terms

  • Carrier Proteins / metabolism
  • Cysteine / metabolism
  • Energy Metabolism*
  • Mitochondria / metabolism*
  • Mitochondrial Membranes / metabolism*
  • Models, Biological
  • Protein Transport
  • Proteins / chemistry
  • Proteins / metabolism*

Substances

  • Carrier Proteins
  • Proteins
  • Cysteine