Portal vein thrombosis as the first sign of nephrotic syndrome

Nat Clin Pract Nephrol. 2008 Jun;4(6):342-5. doi: 10.1038/ncpneph0810. Epub 2008 May 6.

Abstract

Background: A 52-year-old man presented to hospital having experienced abdominal pain, abdominal distention and oliguria for 1 week. An abdominal CT scan revealed thrombosis in the superior mesenteric vein and in the right branch and the trunk of the portal vein.

Investigations: Physical examination, blood and urine analyses, color Doppler ultrasonography and abdominal CT scan.

Diagnosis: Nephrotic syndrome complicated by portal vein thrombosis.

Management: Treatment with batroxobin, low-molecular-weight heparin, prostaglandin E, dipyridamole and methylprednisolone.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / diagnosis
  • Abdominal Pain / etiology
  • Fibrinolytic Agents / therapeutic use
  • Follow-Up Studies
  • Humans
  • Male
  • Mesenteric Vascular Occlusion / diagnostic imaging
  • Mesenteric Vascular Occlusion / drug therapy
  • Mesenteric Vascular Occlusion / etiology*
  • Mesenteric Veins
  • Middle Aged
  • Nephrotic Syndrome / complications*
  • Nephrotic Syndrome / diagnosis*
  • Nephrotic Syndrome / drug therapy
  • Portal Vein*
  • Risk Assessment
  • Severity of Illness Index
  • Thrombolytic Therapy / methods
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vascular Patency / drug effects
  • Venous Thrombosis / diagnostic imaging
  • Venous Thrombosis / drug therapy
  • Venous Thrombosis / etiology*

Substances

  • Fibrinolytic Agents