Abstract
Organocopper reagents smoothly react with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a "double duty" in this novel cascade transformation, which proceeds via an SN2' substitution followed by a subsequent cycloisomerization step.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Catalysis
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Copper / chemistry*
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Heterocyclic Compounds / chemistry*
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Isomerism
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Nitrogen / chemistry*
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Organometallic Compounds / chemistry*
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Temperature*
Substances
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Heterocyclic Compounds
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Organometallic Compounds
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Copper
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Nitrogen