Open chromatin and hypertranscription in embryonic stem cells
- PMID: 18462689
- DOI: 10.1016/j.stem.2008.04.006
Open chromatin and hypertranscription in embryonic stem cells
Abstract
In this issue of Cell Stem Cell, Efroni et al. (2008) use tiling microarrays to reveal genome-wide hypertranscription in mouse embryonic stem cells (ESCs), including expression of normally silent, noncoding regions. Hypertranscription may reflect the unusual "open" structure of ESC chromatin.
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Global transcription in pluripotent embryonic stem cells.Cell Stem Cell. 2008 May 8;2(5):437-47. doi: 10.1016/j.stem.2008.03.021. Cell Stem Cell. 2008. PMID: 18462694 Free PMC article.
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