Ecology and genomics of Bacillus subtilis

Trends Microbiol. 2008 Jun;16(6):269-75. doi: 10.1016/j.tim.2008.03.004. Epub 2008 May 28.


Bacillus subtilis is a remarkably diverse bacterial species that is capable of growth within many environments. Recent microarray-based comparative genomic analyses have revealed that members of this species also exhibit considerable genomic diversity. The identification of strain-specific genes might explain how B. subtilis has become so broadly adapted. The goal of identifying ecologically adaptive genes could soon be realized with the imminent release of several new B. subtilis genome sequences. As we embark upon this exciting new era of B. subtilis comparative genomics we review what is currently known about the ecology and evolution of this species.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Bacillus subtilis* / classification
  • Bacillus subtilis* / genetics
  • Bacillus subtilis* / growth & development
  • Bacillus subtilis* / physiology
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Ecology*
  • Genome, Bacterial
  • Genomics*
  • Nucleic Acid Hybridization
  • Oligonucleotide Array Sequence Analysis
  • Species Specificity


  • Bacterial Proteins