Role of transposable elements in trypanosomatids

Frédéric Bringaud; Elodie Ghedin; Najib M A El-Sayed; Barbara Papadopoulou

doi:10.1016/j.micinf.2008.02.009

Role of transposable elements in trypanosomatids

Microbes Infect. 2008 May;10(6):575-81. doi: 10.1016/j.micinf.2008.02.009. Epub 2008 Feb 21.

Authors

Frédéric Bringaud¹, Elodie Ghedin, Najib M A El-Sayed, Barbara Papadopoulou

Affiliation

¹ Laboratoire de Résonance Magnétique des Systèmes Biologiques, Université Victor Segalen Bordeaux 2, UMR-5536 CNRS, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France. bringaud@u-bordeaux2.fr

PMID: 18467144
DOI: 10.1016/j.micinf.2008.02.009

Abstract

Transposable elements constitute 2-5% of the genome content in trypanosomatid parasites. Some of them are involved in critical cellular functions, such as the regulation of gene expression in Leishmania spp. In this review, we highlight the remarkable role extinct transposable elements can play as the source of potential new functions.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
DNA Transposable Elements / physiology*
DNA, Intergenic / genetics
Evolution, Molecular
Gene Expression Regulation / physiology*
Genome, Protozoan / genetics*
Host-Parasite Interactions / physiology
Leishmania / genetics
Leishmania / physiology
Trypanosoma

Substances

DNA Transposable Elements
DNA, Intergenic