Gastric ulcer treatment: cure of Helicobacter pylori infection without subsequent acid-suppressive therapy: is it effective?

Eur J Gastroenterol Hepatol. 2008 Jun;20(6):489-91. doi: 10.1097/MEG.0b013e3282f427c8.


Whether it is a requirement to continue with anti-secretory therapy following anti-Helicobacter therapy in H. pylori positive gastric ulcers is an important question. As gastric ulcers tend to heal more slowly than duodenal ulcers, may be asymptomatic or only causing mild symptoms and success at curing H. pylori with current fist line therapies is 80% at best, clinicians will likely err on the side of caution and continue acid suppressive therapy to ensure healing of gastric ulcers. This is certainly recommended when dealing with bleeding ulcers.

Publication types

  • Comment
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Anti-Ulcer Agents / therapeutic use*
  • Drug Therapy, Combination
  • Helicobacter Infections / complications
  • Helicobacter Infections / drug therapy*
  • Helicobacter pylori*
  • Humans
  • Proton Pump Inhibitors / therapeutic use
  • Stomach Ulcer / drug therapy*
  • Stomach Ulcer / microbiology*
  • Treatment Outcome


  • Anti-Bacterial Agents
  • Anti-Ulcer Agents
  • Proton Pump Inhibitors