Control of interstitial pneumonia by drip infusion of megadose vitamin C, dehydroepiandrosterone and cortisol. A short review of our experience

In Vivo. 2008 Mar-Apr;22(2):263-7.


Interstitial pneumonia can be controlled by the combined use of a prophylactic antibiotic system and the drip infusion system including megadose vitamin C, dehydroepiandrosterone (D) and cortisol (F), a fortified substitute of 3 adrenocortical elements. The response of patients was satisfying with few side-effects of F. It was shown that an excess of vitamin C improved the therapeutic efficacy of D-F complex, and that D and F improved the immunodeficient state of the host. The benefit of D as an adrenal androgen in immunology found another example in the combined use of cyclosporine A (CS) and glucocorticoid (G) in the kidney transplantation clinic: CS and G helps improve graft take by creating a state of androgen excess, as testified in both humans and mice--an alleviation of immune conflict.

Publication types

  • Review

MeSH terms

  • Ascorbic Acid / administration & dosage*
  • Ascorbic Acid / therapeutic use
  • Dehydroepiandrosterone / administration & dosage*
  • Dehydroepiandrosterone / therapeutic use
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Humans
  • Hydrocortisone / administration & dosage*
  • Hydrocortisone / therapeutic use
  • Infusions, Intravenous
  • Lung Diseases, Interstitial / drug therapy*


  • Dehydroepiandrosterone
  • Ascorbic Acid
  • Hydrocortisone