Exponential growth of new chemicals and evolution of information relevant to risk control

Ann Ist Super Sanita. 2008;44(1):13-5.


The number of new chemicals synthesized and marketed increases exponentially. The database CAS REGISTRY at present contains more than 33 million organic and inorganic substances. However, the little information regarding the potential hazard associated with a large amount of chemicals is an old known problem in the European Union and also in the United States. This critical problem may find a solution in the collaboration of the different involved countries and in a planned task setting at international level. Both in the United States (e.g., the "Gore Initiative") and in European Union (the REACH policy) a big effort has been dedicated to this solution, within standardized procedures and an appropriate collaboration.

Publication types

  • Review

MeSH terms

  • Chemical Industry / legislation & jurisprudence*
  • Chemical Industry / trends
  • Databases as Topic
  • Environmental Pollution / prevention & control*
  • European Union
  • Hazardous Substances / adverse effects
  • Humans
  • Information Systems / organization & administration
  • Inorganic Chemicals* / adverse effects
  • Inorganic Chemicals* / chemical synthesis
  • International Cooperation
  • Occupational Diseases / prevention & control*
  • Organic Chemicals* / adverse effects
  • Organic Chemicals* / chemical synthesis
  • Risk Assessment
  • United States


  • Hazardous Substances
  • Inorganic Chemicals
  • Organic Chemicals