Acute invasive fungal rhinosinusitis: our experience with 19 patients

Eur Arch Otorhinolaryngol. 2009 Jan;266(1):77-82. doi: 10.1007/s00405-008-0694-9. Epub 2008 May 10.

Abstract

Acute invasive fungal rhinosinusitis (AIFR) is a potentially fatal infection that affects immunocompromised patients. Early diagnosis and treatment, including aggressive surgical debridement, antifungal medication, and correction of underlying predisposing factors are essential for recovery. The aim of this study was to review our experience with AIFR. The records of 19 patients histopathologically diagnosed with invasive fungal rhinosinusitis were retrospectively reviewed. Demographic data, presenting symptoms and signs, underlying diseases, and outcomes of the patients are presented and invasive fungal rhinosinusitis is discussed in light of the current literature.

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Aged
  • Antifungal Agents / therapeutic use
  • Aspergillosis / diagnosis
  • Aspergillosis / drug therapy
  • Aspergillosis / immunology
  • Aspergillosis / mortality
  • Child
  • Child, Preschool
  • Cohort Studies
  • Early Diagnosis
  • Female
  • Follow-Up Studies
  • Fungemia / diagnosis*
  • Fungemia / drug therapy
  • Fungemia / microbiology
  • Fungemia / mortality
  • Humans
  • Immunocompromised Host*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Mucormycosis / diagnosis
  • Mucormycosis / drug therapy
  • Mucormycosis / immunology
  • Mucormycosis / mortality
  • Retrospective Studies
  • Rhinitis / diagnosis*
  • Rhinitis / drug therapy
  • Rhinitis / immunology
  • Rhinitis / mortality
  • Risk Assessment
  • Severity of Illness Index
  • Sinusitis / diagnosis*
  • Sinusitis / drug therapy
  • Sinusitis / immunology
  • Sinusitis / mortality
  • Survival Analysis
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult

Substances

  • Antifungal Agents