Repeated recovery of Staphylococcus saprophyticus from the urogenital tracts of women: persistence vs. recurrence

Infect Dis Obstet Gynecol. 1995;2(5):218-22. doi: 10.1155/S1064744995000056.

Abstract

Objective: The purpose of this study was to determine whether colonization was persistent or recurrent in a small group of women who had repeated recovery of Staphylococcus saprophyticus from their urogenital tracts.

Methods: Paired isolates of S. saprophyticus from each of the study subjects were genotypically typed by plasmid fingerprinting and comparison of chromosomal-DNA restriction fragment-length polymorphism patterns by field-inversion gel electrophoresis (FIGE) and contour-clamped homogenous electric-field (CHEF) electrophoresis.

Results: All isolates of S. saprophyticus from the study subjects were classified as genetically unique by each of the typing methods.

Conclusions: The subjects experienced recurrent colonization with different isolates of S. saprophyticus. These findings may have broader implications regarding the pathogenesis and recurrence of S. saprophyticus urinary-tract infection.