The effectiveness of mineral trioxide aggregate, calcium hydroxide and formocresol for pulpotomies in primary teeth

Int Endod J. 2008 Jul;41(7):547-55. doi: 10.1111/j.1365-2591.2008.01377.x. Epub 2008 May 12.

Abstract

Aim: To compare the effectiveness of mineral trioxide aggregate (MTA), calcium hydroxide (CH) and formocresol (FC) as pulp dressing agents in carious primary teeth.

Methodology: Forty-five primary mandibular molars with dental caries in 23 children [AUTHOR QUERY: How many children?] between 5 and 9 years old were treated by a conventional pulpotomy technique. The teeth were randomly assigned to the experimental (CH or MTA) or control (FC) groups. After coronal pulp removal and haemostasis, remaining pulp tissue was covered with MTA paste or CH powder in the experimental groups. In the control group, diluted FC was placed with a cotton pellet over the pulp tissue for 5 min and removed; the pulp tissue was then covered with zinc oxide-eugenol (ZOE) paste. All teeth were restored with reinforced ZOE base and resin modified glass-ionomer cement. Clinical and radiographic successes and failures were recorded at 3, 6, 12, 18 and 24 month follow-up.

Results: Forty-three teeth were available for follow-up. In the FC and MTA groups, 100% of the available teeth were clinically and radiographically successful at all follow-up appointments; dentine bridge formation could be detected in 29% of the teeth treated with MTA. In the CH group, 64% of the teeth presented clinical and radiographic failures detected throughout the follow-up period, and internal resorption was a frequent radiographic finding.

Conclusions: Mineral trioxide aggregate was superior to CH and equally as effective as FC as a pulpotomy dressing in primary mandibular molars. Internal resorption was the most common radiographic finding up to 24 month after pulpotomies performed with CH.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aluminum Compounds / pharmacology*
  • Calcium Compounds / pharmacology*
  • Calcium Hydroxide / pharmacology
  • Child
  • Child, Preschool
  • Dental Pulp / drug effects
  • Dentin, Secondary / metabolism
  • Drug Combinations
  • Female
  • Formocresols / pharmacology
  • Humans
  • Male
  • Oxides / pharmacology*
  • Pulpotomy / adverse effects
  • Pulpotomy / methods*
  • Root Canal Filling Materials / pharmacology*
  • Root Resorption / etiology
  • Silicates / pharmacology*
  • Tooth, Deciduous

Substances

  • Aluminum Compounds
  • Calcium Compounds
  • Drug Combinations
  • Formocresols
  • Oxides
  • Root Canal Filling Materials
  • Silicates
  • mineral trioxide aggregate
  • formocresol
  • Calcium Hydroxide