Fournier's gangrene: evaluation of 68 patients and analysis of prognostic variables

J Postgrad Med. 2008 Apr-Jun;54(2):102-5. doi: 10.4103/0022-3859.40775.


Context: Fournier's gangrene (FG) is a rapidly progressing acute gangrenous infection of the anorectal and urogenital area.

Aims: The objectives of this study were to investigate patients with FG and to determine risk factors that affect mortality.

Settings and design: Retrospective clinical study.

Materials and methods: Clinical presentations and outcomes of surgical treatments were evaluated in 68 patients with FG.

Statistical analysis used: Chi-square, Student's t -test, and logistic regression test.

Results: Mean age of patients was 54 and female-to-male ratio was 9:59. Among the predisposing factors, diabetes mellitus (DM) was the most common ( n =24, 35.3%), and sepsis on admission was detected in 31 (45.6%) and 15 (22.1%) patients, respectively. Seven (10.3%) patients died. Using logistic regression test, Fournier's Gangrene Severity Index (FGSI)> 9, DM and sepsis on admission were found as prognostic factors.

Conclusions: FG has a high mortality rate, especially in patients with DM and sepsis. An FGSI value> 9 indicates high mortality rate.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Fournier Gangrene / complications*
  • Fournier Gangrene / diagnosis*
  • Fournier Gangrene / mortality
  • Fournier Gangrene / therapy
  • Humans
  • Length of Stay
  • Logistic Models
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prognosis
  • Retrospective Studies
  • Risk Factors
  • Sepsis / complications*
  • Severity of Illness Index
  • Time Factors
  • Treatment Outcome