Abstract
We report the 1st case of Bordetella hinzii septicemia associated with Epstein-Barr virus viremia and lymphoma. B. hinzii identification necessitated cellular fatty acid analysis by gas-liquid chromatography and 16S rRNA gene sequencing. Isolates were resistant to many antimicrobials. Resistance and diagnostic challenges complicated management and contributed to mortality.
MeSH terms
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Adult
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use
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Bordetella / chemistry
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Bordetella / classification
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Bordetella / genetics
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Bordetella / isolation & purification*
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Bordetella Infections / diagnosis*
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DNA, Bacterial / genetics
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DNA, Ribosomal / genetics
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Drug Resistance, Multiple, Bacterial
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Epstein-Barr Virus Infections / complications*
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Epstein-Barr Virus Infections / immunology
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Fatal Outcome
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Fatty Acids / analysis
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Female
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Genes, rRNA
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Herpesvirus 4, Human / isolation & purification*
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Humans
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Lymphoma, B-Cell / immunology
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Lymphoma, B-Cell / virology*
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Microbial Sensitivity Tests
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RNA, Bacterial / genetics
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RNA, Ribosomal, 16S / genetics
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Sepsis / microbiology*
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Sequence Analysis, DNA
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Viremia / immunology
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Viremia / virology*
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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DNA, Ribosomal
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Fatty Acids
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RNA, Bacterial
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RNA, Ribosomal, 16S