Bordetella hinzii septicemia in association with Epstein-Barr virus viremia and an Epstein-Barr virus-associated diffuse large B-cell lymphoma

Diagn Microbiol Infect Dis. 2008 Aug;61(4):484-6. doi: 10.1016/j.diagmicrobio.2008.03.013. Epub 2008 May 14.

Abstract

We report the 1st case of Bordetella hinzii septicemia associated with Epstein-Barr virus viremia and lymphoma. B. hinzii identification necessitated cellular fatty acid analysis by gas-liquid chromatography and 16S rRNA gene sequencing. Isolates were resistant to many antimicrobials. Resistance and diagnostic challenges complicated management and contributed to mortality.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Bordetella / chemistry
  • Bordetella / classification
  • Bordetella / genetics
  • Bordetella / isolation & purification*
  • Bordetella Infections / diagnosis*
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / genetics
  • Drug Resistance, Multiple, Bacterial
  • Epstein-Barr Virus Infections / complications*
  • Epstein-Barr Virus Infections / immunology
  • Fatal Outcome
  • Fatty Acids / analysis
  • Female
  • Genes, rRNA
  • Herpesvirus 4, Human / isolation & purification*
  • Humans
  • Lymphoma, B-Cell / immunology
  • Lymphoma, B-Cell / virology*
  • Microbial Sensitivity Tests
  • RNA, Bacterial / genetics
  • RNA, Ribosomal, 16S / genetics
  • Sepsis / microbiology*
  • Sequence Analysis, DNA
  • Viremia / immunology
  • Viremia / virology*

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • DNA, Ribosomal
  • Fatty Acids
  • RNA, Bacterial
  • RNA, Ribosomal, 16S