Cardiac complications in Whipple's disease

Eur J Echocardiogr. 2008 May;9(3):426-7. doi: 10.1093/ejechocard/jen022. Epub 2008 Mar 30.


Whipple's disease or intestinal lipodystrophy is an infection induced by Tropheryma whipplei. It is rare with an estimated incidence of 0.4 per million. Symptoms are arthropathy, weight loss, and diarrhoea, but other organs notably the central nervous system may be affected. We demonstrate a case of cardiac complications in Whipple's disease. The patient presented with endocardial infiltrations on TEE examinations and heart failure and improved after antibiotic treatment.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Heart Diseases / diagnostic imaging*
  • Heart Diseases / drug therapy
  • Heart Diseases / etiology
  • Humans
  • Middle Aged
  • Ultrasonography
  • Whipple Disease / complications*
  • Whipple Disease / drug therapy