A paradigm shift to prevent HIV drug resistance

PLoS Med. 2008 May 20;5(5):e111. doi: 10.1371/journal.pmed.0050111.

Abstract

David Bangsberg discusses a new observational cohort study in nine countries in southern Africa that compares CD4 counts versus adherence to antiretroviral drugs for predicting virologic failure.

Publication types

  • Comment
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-HIV Agents / therapeutic use*
  • Anti-Retroviral Agents / therapeutic use*
  • CD4-Positive T-Lymphocytes / cytology
  • Drug Resistance, Viral*
  • HIV / genetics
  • HIV Infections / drug therapy*
  • HIV Infections / pathology*
  • Humans
  • Monitoring, Physiologic / methods
  • Patient Compliance*
  • RNA, Viral / analysis
  • Treatment Outcome
  • Viral Load

Substances

  • Anti-HIV Agents
  • Anti-Retroviral Agents
  • RNA, Viral