Atypical cystic meningioma overexpressing AQP1 in early infancy: case report with literature review

Acta Paediatr. 2008 Aug;97(8):1145-9. doi: 10.1111/j.1651-2227.2008.00877.x. Epub 2008 May 21.

Abstract

Meningiomas in early infancy are rare lesions, worth to be reported for their exceptional occurrence. The authors report a case of an 11-month-old female child with asymmetric macrocephaly due to the presence of a cystic atypical meningioma associated to bilateral subdural collections.

Conclusion: This unusual and unique case of atypical cystic meningioma in early infancy showed a high positivity to immunostaining of aquaporin 1, and this pattern could correlate with the coexistence both of cysts and subdural collections.

Publication types

  • Case Reports

MeSH terms

  • Antigens, CD34 / genetics
  • Aquaporin 1 / genetics*
  • Aquaporin 4 / genetics*
  • Biomarkers
  • Craniotomy
  • Cysts / genetics*
  • Cysts / pathology*
  • Cysts / surgery
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Imaging
  • Meningeal Neoplasms / genetics*
  • Meningeal Neoplasms / pathology*
  • Meningeal Neoplasms / surgery

Substances

  • AQP1 protein, human
  • AQP4 protein, human
  • Antigens, CD34
  • Aquaporin 4
  • Biomarkers
  • Aquaporin 1