Interplay of JH, 20E and biogenic amines under normal and stress conditions and its effect on reproduction

J Insect Physiol. 2008 Jun;54(6):902-8. doi: 10.1016/j.jinsphys.2008.04.004. Epub 2008 Apr 11.

Abstract

Juvenile hormone (JH) and 20-hydroxyecdysone (20E) are well known to play a gonadotropic role in adult insects. In Drosophila the mechanism of reciprocal regulation of JH and 20E is shown to be responsible for their proper balance. Dopamine is a mediator in this JH and 20E interplay. A proper balance between JH and 20E is crucial for the normal progress of oogenesis. An imbalance of gonadotropins leads to reproductive defects: a rise in JH titre leads to oviposition arrest, a rise in 20E level, to the degradation of vitellogenic oocytes. Upon a change in the level of one of the gonadotropins, the balance is restored owing to the relative change in the titre of the other.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biogenic Monoamines / metabolism*
  • Drosophila melanogaster / physiology*
  • Ecdysterone / metabolism*
  • Female
  • Juvenile Hormones / metabolism*
  • Oviparity*

Substances

  • Biogenic Monoamines
  • Juvenile Hormones
  • Ecdysterone