Associations of acculturation and socioeconomic status with subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis

Am J Public Health. 2008 Nov;98(11):1963-70. doi: 10.2105/AJPH.2007.123844. Epub 2008 May 29.

Abstract

Objectives: We assessed whether markers of acculturation (birthplace and number of US generations) and socioeconomic status (SES) are associated with markers of subclinical cardiovascular disease-carotid artery plaque, internal carotid intima-media thickness, and albuminuria-in 4 racial/ethnic groups.

Methods: With data from the Multi-Ethnic Study of Atherosclerosis (n = 6716 participants aged 45-84 years) and race-specific binomial regression models, we computed prevalence ratios adjusted for demographics and traditional cardiovascular risk factors.

Results: The adjusted US- to foreign-born prevalence ratio for carotid plaque was 1.20 (99% confidence interval [CI] = 0.97, 1.39) among Whites, 1.91 (99% CI = 0.94, 2.94) among Chinese, 1.62 (99% CI = 1.28, 2.06) among Blacks, and 1.23 (99% CI = 1.15, 1.31) among Hispanics. Greater carotid plaque prevalence was found among Whites, Blacks, and Hispanics with a greater number of generations with US residence (P < .001) and among Whites with less education and among Blacks with lower incomes. Similar associations were observed with intima-media thickness. There was also evidence of an inverse association between albuminuria and SES among Whites and Hispanics.

Conclusions: Greater US acculturation and lower SES were associated with a higher prevalence of carotid plaque and greater intima-media thickness but not with albuminuria. Maintenance of healthful habits among recent immigrants should be encouraged.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Acculturation*
  • African Americans / statistics & numerical data
  • Aged
  • Aged, 80 and over
  • Albuminuria / diagnosis*
  • Albuminuria / ethnology*
  • Asian Americans / statistics & numerical data
  • Atherosclerosis / ethnology*
  • Atherosclerosis / physiopathology
  • Biomarkers
  • Carotid Artery Diseases / diagnosis*
  • Carotid Artery Diseases / ethnology*
  • Carotid Artery, Internal / pathology
  • Cohort Studies
  • Female
  • Health Status Disparities
  • Hispanic or Latino / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Prospective Studies
  • Social Class*
  • United States / epidemiology
  • Whites / statistics & numerical data

Substances

  • Biomarkers