Characterization of the full-length genomic sequences of vesicular stomatitis Cocal and Alagoas viruses

Arch Virol. 2008;153(7):1353-7. doi: 10.1007/s00705-008-0113-y. Epub 2008 May 30.


In Brazil and Argentina, vesicular stomatitis (VS) is caused by distinct viral strains serologically related to the classical vesicular stomatitis virus Indiana (VSIV), namely VS Indiana-2 (VSIV-2) and VS Indiana-3 (VSIV-3). Here we describe the full-length genomic sequences and organization of the prototype strains of VSIV-2 Cocal virus (COCV) and VSIV-3 Alagoas virus (VSAV). These viruses showed similar genomic organizations to VSIV field isolates except that the non-structural C'/C proteins, markedly conserved throughout the vesiculoviruses, were absent in VSAV. Phylogenetic analyses consistently grouped COCV, VSAV and VSIV in a monophyletic group distinct from VSNJV, supporting the classification of these viruses within the Indiana serogroup.

MeSH terms

  • Animals
  • Animals, Domestic / virology
  • Argentina
  • Base Sequence
  • Brazil
  • Gene Order
  • Genome, Viral*
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Viral / genetics*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Vesicular Stomatitis / virology
  • Vesiculovirus / genetics*
  • Viral Proteins / genetics


  • RNA, Viral
  • Viral Proteins

Associated data

  • GENBANK/EU373657
  • GENBANK/EU373658