Clinico-radiological profile of new smear positive pulmonary tuberculosis cases among young adult and elderly people in a tertiary care hospital at Deheradun (Uttarakhand)

Indian J Tuberc. 2008 Apr;55(2):84-90.


Setting: Patients of pulmonary tuberculosis (TB) attending the out and in patient department of pulmonary medicine, Himalayan Institute of Medical Sciences (HIMS), a post graduate institute and a large tertiary care center in Dehradun.

Objective: To compare the clinico-radiological pattern of pulmonary tuberculosis in the young adult (18-59 years) and elderly (> or = 60 years) patients.

Design: Prospective observational study of pulmonary and associated extra pulmonary tuberculosis cases, diagnosed between October 2005 to September 2006 in pulmonary medicine department of HIMS.

Result: Mean age of young adult and elderly patients was 35.71 +/- 5.7 years and 68.57 +/- 3.03 years respectively. Elderly patients had a higher number of co-morbidities like diabetes mellitus, hypertension, and malignancy. Tuberculin positivity was less among elderly patients (36.0%) as compared to young adults (65.9%). Hemoptysis (29.5% vs. 6%), fever (95.4% vs. 76%) and night sweats (54.5% vs. 18.0%) were significantly higher in the young adult patients than the elderly. As for roentgenographic abnormalities, a higher involvement of lower zone (24.0% vs. 7.9%) and far advanced lesions (32.0% vs. 14.7%) were seen in the elderly patients as compared to young adults. The elderly showed a higher frequency of TB related mortality (8% vs. 1.1%) and associated extra pulmonary involvement (40% vs. 7%).

Conclusion: Young adults are more likely to have hemoptysis, night sweats and positive PPD response while lower lung field involvement is more common in elderly.

Publication types

  • Comparative Study

MeSH terms

  • Academic Medical Centers
  • Adult
  • Age Factors
  • Aged
  • Comorbidity
  • Diabetes Mellitus / epidemiology
  • Female
  • Fever / epidemiology
  • Hemoptysis / epidemiology
  • Humans
  • Hypertension / epidemiology
  • India / epidemiology
  • Male
  • Neoplasms / epidemiology
  • Prospective Studies
  • Radiography
  • Survival Rate
  • Tuberculin Test / statistics & numerical data
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / diagnostic imaging
  • Tuberculosis, Pulmonary / epidemiology*