Subdiffusion in Peptides Originates From the Fractal-Like Structure of Configuration Space

Phys Rev Lett. 2008 May 9;100(18):188103. doi: 10.1103/PhysRevLett.100.188103. Epub 2008 May 6.

Abstract

Molecular dynamics simulation of oligopeptide chains reveals configurational subdiffusion at equilibrium extending from 10(-12) to 10(-8) s. Trap models, involving a random walk with a distribution of waiting times, cannot account for the subdiffusion, which is found rather to arise from the fractal-like structure of the accessible configuration space.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Simulation
  • Diffusion
  • Fractals*
  • Models, Chemical*
  • Oligopeptides / chemistry*
  • Protein Conformation
  • Thermodynamics

Substances

  • Oligopeptides