Cerebral mycetoma with cranial osteomyelitis

J Neurosurg Pediatr. 2008 Jun;1(6):493-5. doi: 10.3171/PED/2008/1/6/493.


Craniocerebral maduromycetoma is extremely rare. The authors describe a case of maduromycetoma involving the left parietal cortex, bone, and subcutaneous tissue in a young male farm laborer who presented with left parietal scalp swelling that had progressed into a relentlessly discharging sinus. Computed tomography (CT) scanning of his brain revealed osteomyelitis of the parietal bone with an underlying homogeneously enhancing tumor. Intraoperatively, the mass was revealed to be a black lesion involving the bone, dura mater, and underlying cerebral cortex. It was friable and separated from the surrounding brain by a thick gliotic scar. Gross-total excision was performed, and the patient was placed on a 6-week regimen of itraconazole. To the authors' knowledge, this is the first instance of cerebral mycetoma with CT findings reported in the literature.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Brain Diseases / diagnosis*
  • Brain Diseases / microbiology
  • Brain Diseases / therapy
  • Central Nervous System Fungal Infections / diagnosis*
  • Central Nervous System Fungal Infections / microbiology
  • Central Nervous System Fungal Infections / therapy
  • Humans
  • Madurella*
  • Male
  • Mycetoma / diagnosis*
  • Mycetoma / therapy
  • Osteomyelitis / diagnosis*
  • Osteomyelitis / microbiology
  • Osteomyelitis / therapy
  • Parietal Bone*