One-pot oxidative esterification and amidation of aldehydes

Chemistry. 2008;14(21):6302-15. doi: 10.1002/chem.200800353.

Abstract

During recent years, the direct transformation of aldehydes into esters or amides has developed into a vigorous research area and powerful one-pot oxidative esterification and amidation procedures have been reported. Several concepts that are often complementary in substrate scope, functional group tolerance, and reaction outcome have emerged, thus providing a wide range of alternatives to classical ester and amide synthesis via carboxylic acid intermediates.

Publication types

  • Review

MeSH terms

  • Aldehydes / chemistry*
  • Amides / chemistry*
  • Esterification
  • Oxidation-Reduction

Substances

  • Aldehydes
  • Amides