Peripheral neuropathy complicating primary hyperoxaluria

J Neurol Sci. 1976 Oct;29(2-4):343-9. doi: 10.1016/0022-510x(76)90183-0.


A patient with chronic renal disease due to primary hyperoxaluria developed a rapidly progressing motor neuropathy with marked impairment of nerve conduction. Pathological studies demonstrated the presence of both axonal degeneration and segmental demyelination, together with the presence of oxalate crystals within axons. It is suggested that the development of peripheral neuropathy complicating hyperoxaluria is a consequence of the increased life-span mad possible by haemodialysis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carbohydrate Metabolism, Inborn Errors / complications*
  • Humans
  • Kidney Failure, Chronic / complications*
  • Male
  • Oxalates / urine*
  • Peripheral Nerves / pathology
  • Peripheral Nervous System Diseases / etiology*
  • Peripheral Nervous System Diseases / pathology
  • Syndrome


  • Oxalates