Cement spacer loaded with antibiotics for infected implants of the hip joint

J Arthroplasty. 2009 Jan;24(1):83-9. doi: 10.1016/j.arth.2004.06.032. Epub 2007 Feb 1.

Abstract

It is difficult to treat infected implants of the hip joints. Such treatment involves immeasurable physical and psychological suffering of the patients. We used antibiotic-impregnated cement spacers in 17 cases of infection after total hip arthroplasty and bipolar arthroplasty with good clinical results. We thoroughly removed any foreign material and formed an antibiotic-impregnated cement spacer into a similar shape as that of the implants. A cement spacer enables high-concentration antibiotics to act on infected sites. Also, it can prevent leg length discrepancy and atrophy of bones or muscles. Although cement spacers have been reported to have problems regarding shape and strength, we achieved good results with a cement spacer mold in the present study. No recurring infection has been found at a mean follow-up period of 3 years and 2 months.

Publication types

  • Retracted Publication

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use*
  • Arthroplasty, Replacement, Hip / instrumentation*
  • Arthroplasty, Replacement, Hip / methods*
  • Bone Cements*
  • Dose-Response Relationship, Drug
  • Drug Delivery Systems / methods
  • Female
  • Follow-Up Studies
  • Gentamicins / administration & dosage
  • Gentamicins / therapeutic use
  • Hip Joint / microbiology*
  • Hip Prosthesis*
  • Humans
  • Male
  • Middle Aged
  • Prosthesis-Related Infections / drug therapy*
  • Prosthesis-Related Infections / prevention & control
  • Secondary Prevention
  • Treatment Outcome
  • Vancomycin / administration & dosage
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Bone Cements
  • Gentamicins
  • Vancomycin