Abstract
We report a case of fatal myocarditis in a newborn infant who was infected with a human enterovirus detected by throat culture and RT-PCR for viral RNA in plasma. Whole genome sequence analysis revealed the virus to be a genomic chimera that likely arose from recombination between coxsackievirus B3 and two recently identified enteroviruses, EV 86 and EV97.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Enterovirus B, Human / isolation & purification*
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Enterovirus Infections / diagnosis*
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Fatal Outcome
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Genome, Viral
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Humans
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Infant, Newborn
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Male
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Molecular Sequence Data
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Myocarditis / virology*
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Pharynx / virology
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Plasma / virology
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RNA, Viral / genetics
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Recombination, Genetic
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Reverse Transcriptase Polymerase Chain Reaction
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Sequence Analysis, DNA
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Virus Cultivation