Analysis of protein surface patterns by pocket similarity network

Protein Pept Lett. 2008;15(5):448-55. doi: 10.2174/092986608784567474.

Abstract

In this work, in order to reveal protein surface patterns in a systems biology framework, we analyze the similarity among the surface cavities by investigating the features of the pocket similarity network such as the community structure, the small-world property, the scale-free characteristic, and the hubs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology / methods*
  • Protein Conformation*
  • Proteins / chemistry*
  • Structural Homology, Protein
  • Surface Properties

Substances

  • Proteins