[Abrikossoff's tumor: about one case of inter-mammary cutaneous localization and review of literature]

Ann Chir Plast Esthet. 2008 Dec;53(6):521-5. doi: 10.1016/j.anplas.2008.03.002. Epub 2008 Jun 9.
[Article in French]


Subject: Our report concerns a large inter-mammary cutaneous Abrikossoff tumor on a 41-year-old female patient, which has prompted us to review the literature.

Case: It was a low pre-sternal skin tumor; CT-Scanning showed a homogeneous mass 5 cm high, 4 cm wide and 4 cm deep. Total tumoral included the right pectoralis major muscle aponeurosis. The skin defect was closed using a V-Y local plasty. Histologic examination revealed no sign of malignity.

Discussion: Abrikossoff tumors (or granular cell tumors) are rare ubiquity tumors locating preferably in ENT and oral cavity mucosa. They develop between 20 and 60 and more often concern women. They are overwhelmingly single and benign but on occasion multifocal or malignant. Immunohistochemistry points to a schwannian origin. Treatment is exclusively surgical. Skin closure is by direct suture, skin grafting or local plasty. The use of flaps is not advised as it may delay local recidivation diagnosis. The literature reports one single other case of chest wall location.

Conclusion: Abrikossoff tumors require complete exeresis and mandatory histological examination into possible signs of malignity. The risk of recidivation warrants long-term surveillance.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Female
  • Granular Cell Tumor / diagnostic imaging
  • Granular Cell Tumor / surgery*
  • Humans
  • Radiography
  • Skin Neoplasms / diagnostic imaging
  • Skin Neoplasms / surgery*
  • Sternum
  • Treatment Outcome