Phenotypes of cells with cytoskeletal mutations

Curr Opin Cell Biol. 1991 Feb;3(1):18-26. doi: 10.1016/0955-0674(91)90161-q.


Analysis of the cytoskeleton has relied heavily on the identification of phenotypic alterations associated with mutations in cytoskeletal components. This approach has led to important findings for specific proteins. The last year has also strengthened the view that certain functions of the cytoskeleton are safeguarded by the presence of multiple protein forms.

Publication types

  • Review

MeSH terms

  • Actin Cytoskeleton
  • Animals
  • Cytoskeleton*
  • Humans
  • Intermediate Filaments
  • Mutation*
  • Phenotype