The expanding universe of hypoxia

J Mol Med (Berl). 2008 Jul;86(7):739-46. doi: 10.1007/s00109-008-0364-9. Epub 2008 Jun 13.

Abstract

Reduced oxygen availability (hypoxia) is sensed and transduced into changes in the activity or expression of cellular macromolecules. These responses impact on virtually all areas of biology and medicine. In this meeting report, we summarize major developments in the field that were presented at the 2008 Keystone Symposium on Cellular, Physiological, and Pathogenic Responses to Hypoxia.

Publication types

  • Congress

MeSH terms

  • Animals
  • Cell Differentiation
  • Cell Hypoxia*
  • Humans
  • Hypoxia-Inducible Factor 1 / metabolism
  • Ischemia / metabolism
  • Neoplasms / metabolism
  • Oxidation-Reduction
  • Oxygen / metabolism*
  • Reactive Oxygen Species / metabolism

Substances

  • Hypoxia-Inducible Factor 1
  • Reactive Oxygen Species
  • Oxygen