Treatment of disseminated superficial actinic porokeratosis with topical diclofenac gel: a case series

J Eur Acad Dermatol Venereol. 2008 Nov;22(11):1343-5. doi: 10.1111/j.1468-3083.2008.02842.x. Epub 2008 Jun 11.

Abstract

Disseminated superficial actinic porokeratosis (DSAP) is the most common of the of five clinical variants of porokeratosis. These are disorders of keratinization and the distinctive pathological feature is the cornoid lamella at the margin. DSAP usually manifests in the third or fourth decades of life with a female preponderance and with multiple lesions over sun-exposed areas. A diverse range of treatments is employed though evidence of efficacy remains largely anecdotal. We report a series of eight patients with DSAP treated with 3% diclofenac gel (Solaraze gel).

MeSH terms

  • Administration, Topical
  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Diclofenac / administration & dosage
  • Diclofenac / therapeutic use*
  • Female
  • Gels
  • Humans
  • Keratosis, Actinic / drug therapy*
  • Male
  • Middle Aged

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Gels
  • Diclofenac