Endoplasmic reticulum quality control and the unfolded protein response: insights from plants

Traffic. 2008 Sep;9(10):1581-8. doi: 10.1111/j.1600-0854.2008.00780.x. Epub 2008 Jun 28.


Protein quality control (QC) within the endoplasmic reticulum and the related unfolded protein response (UPR) pathway of signal transduction are major regulators of the secretory pathway, which is involved in virtually any aspect of development and reproduction. The study of plant-specific processes such as pathogen response, seed development and the synthesis of seed storage proteins and of particular toxins is providing novel insights, with potential implications for the general recognition events and mechanisms of action of QC and UPR.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Endoplasmic Reticulum / metabolism*
  • Endoplasmic Reticulum / physiology
  • Plant Physiological Phenomena*
  • Plant Proteins / metabolism*
  • Protein Folding
  • Secretory Pathway / physiology
  • Signal Transduction
  • Stress, Physiological / physiology


  • Plant Proteins