What is the contents of the magic draft IVIg?

Autoimmun Rev. 2008 Jun;7(6):435-9. doi: 10.1016/j.autrev.2008.04.012. Epub 2008 May 2.


Intravenous immunoglobulins (IVIg) consist of IgG concentrated from pooled plasma of numerous donors. Their contents is variable, depending in part on the method of preparation. Natural antibodies and natural autoantibodies are prominent in these preparations and their function. Among these, are the idiotype (Id)/anti-Id dimers. Attention has recently been paid to Fc-gamma receptors and sialylation of the IgG from IVIg.

Publication types

  • Review

MeSH terms

  • Autoantibodies / blood
  • Autoantibodies / immunology*
  • Humans
  • Immunoglobulin Fc Fragments / metabolism
  • Immunoglobulin G / blood
  • Immunoglobulin G / immunology
  • Immunoglobulin Idiotypes / immunology
  • Immunoglobulins, Intravenous / blood
  • Immunoglobulins, Intravenous / immunology*
  • Immunoglobulins, Intravenous / metabolism
  • Receptors, IgG / metabolism


  • Autoantibodies
  • Immunoglobulin Fc Fragments
  • Immunoglobulin G
  • Immunoglobulin Idiotypes
  • Immunoglobulins, Intravenous
  • Receptors, IgG