@neuLink: a service-oriented application for biomedical knowledge discovery

Stud Health Technol Inform. 2008;138:165-72.

Abstract

We introduce the architecture of @neuLink, a service-oriented environment for biomedical knowledge discovery which has been developed in the course of EU Integrated Project @neurIST. The application integrates data from databases with information extracted from unstructured text sources. Moreover, @neuLink supports the analysis of primary biomolecular data associated with individual patients and thus enables the interpretation of molecular data inside a clinical research environment. Based on an assembly of data services, @neuLink interacts with the complex @neurIST grid infrastructure through a dedicated data access and data mediation service. Data types integrated by @neuLink are covering the entire span of biomolecular entities: from gene names in text to entries in EntrezGene; from mentions of drugs to Drugbank, from information on allelic variants in scientific literature to entries in dbSNP. The architecture of @neuLink allows easy integration of other webservice-based applications and thus the spectrum of analysis capabilities of @neuLink can be extended following the requirements of the users of the @neurIST system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Artificial Intelligence*
  • Austria
  • Computational Biology / methods
  • Computational Biology / organization & administration*
  • Computer Systems*
  • Database Management Systems
  • Databases as Topic
  • Decision Support Systems, Clinical / organization & administration*
  • Decision Support Techniques
  • European Union
  • Germany
  • Humans
  • Information Storage and Retrieval / methods
  • Molecular Biology / organization & administration*