Modest membrane hydrogen bonds deliver rich results

Nat Chem Biol. 2008 Jul;4(7):393-4. doi: 10.1038/nchembio0708-393.


The significance of hydrogen bonds in protein structure was recognized as early as 1936 by Mirsky and Pauling, and the importance of hydrogen bonds in water-soluble proteins has since been studied extensively. Now a new paper takes an important step forward in characterizing the energetic significance of hydrogen bonds in membrane-soluble proteins.

Publication types

  • News

MeSH terms

  • Hydrogen Bonding
  • Membrane Proteins / chemistry*
  • Protein Conformation
  • Solubility
  • Thermodynamics
  • Water / chemistry


  • Membrane Proteins
  • Water