Lobular carcinoma in situ

Eur J Cancer Prev. 2008 Aug;17(4):312-6. doi: 10.1097/CEJ.0b013e3282f75e5d.

Abstract

The diagnosis of lobular carcinoma in situ (LCIS) provokes considerable anxiety in patients owing to misconceptions about this diagnosis. Initially LCIS was considered a premalignant lesion, but it is now a marker of increased risk. The number of women diagnosed with LCIS has increased in recent years most likely owing to more rigorous breast cancer screening. Implications of this diagnosis and management options are discussed in this review.

Publication types

  • Review

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Biopsy, Needle
  • Breast Neoplasms / mortality
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / therapy
  • Carcinoma in Situ / mortality
  • Carcinoma in Situ / pathology*
  • Carcinoma in Situ / therapy
  • Carcinoma, Lobular / mortality
  • Carcinoma, Lobular / pathology*
  • Carcinoma, Lobular / therapy
  • Cell Transformation, Neoplastic / pathology
  • Combined Modality Therapy
  • Female
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Monitoring, Physiologic / methods
  • Neoplasm Staging
  • Precancerous Conditions / pathology*
  • Prognosis
  • Risk Assessment
  • Survival Analysis