Guidelines for the diagnosis of ocular sarcoidosis

Ocul Immunol Inflamm. 2008 May-Jun;16(3):77-81. doi: 10.1080/09273940802051100.

Abstract

Purpose: To delineate features of ocular sarcoidosis.

Methods: Comparison of the old and new Japanese guidelines for diagnosing ocular sarcoidosis by review of the medical records of 100 sarcoidosis patients and 147 patients with non-sarcoidosis uveitis.

Results: The overall diagnostic sensitivity and specificity for the old guidelines were 80.0% and 45.6%; sensitivity and specificity for the new guidelines were 84.0% and 83.0%. Positive and negative predictive values and the likelihood ratios for a positive and negative test result improved. The new guidelines achieved more than 80% specificity for all categories.

Conclusion: The new guidelines allow easier distinction of ocular sarcoidosis.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Eye Diseases / diagnosis*
  • Humans
  • Likelihood Functions
  • Medical Records
  • Ophthalmology / trends
  • Practice Guidelines as Topic / standards*
  • Predictive Value of Tests
  • ROC Curve
  • Retrospective Studies
  • Sarcoidosis / diagnosis*
  • Sensitivity and Specificity
  • Uveitis / diagnosis
  • Uveitis / etiology