Traffic, outdoor air pollution, and asthma

Immunol Allergy Clin North Am. 2008 Aug;28(3):577-88, viii-ix. doi: 10.1016/j.iac.2008.03.008.


The epidemiology of asthma and outdoor air pollution has shown that respiratory health effects can vary in relation to different emission sources, types of pollutants, underlying nutritional status, medication use, and genetic polymorphisms. Using sophisticated exposure assessment methods in conjunction with clinical tests and biomarkers that provide mechanistic information, the study of outdoor epidemiology and asthma has evolved into a complex multidisciplinary field. This article presents an overview of the mechanisms by which outdoor air pollution and traffic-related emissions lead to changes in respiratory health and lung function in subjects with asthma.

Publication types

  • Review

MeSH terms

  • Air Pollution / adverse effects*
  • Asthma / etiology*
  • Environmental Exposure / adverse effects*
  • Humans
  • Lung / physiopathology
  • Vehicle Emissions*


  • Vehicle Emissions