Estimated glomerular filtration rate and renal function

Ann Thorac Surg. 2008 Jul;86(1):1-3. doi: 10.1016/j.athoracsur.2008.05.007.

Abstract

Glomerular filtration rate (GFR) is an important clinical indicator of kidney function. It can be used as an independent predictor of long-term survival after cardiac surgery. Definition, methods of measurement, and corrected value by body surface area are briefly introduced in this paper. Details of the calculation of estimated GFR (eGFR) by Levey's formula with serum creatinine, age, gender, and race are offered. The relationship between estimated GFR and the four factors is shown graphically and discussed. An eGFR/creatinine conversion table for individual patients derived from the eGFR equation with clinically significant cutpoints is given, which can be used by physicians as a pragmatic reference.

Publication types

  • Comment

MeSH terms

  • Acute Kidney Injury / physiopathology
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Body Surface Area
  • Creatinine / blood*
  • Female
  • Glomerular Filtration Rate / physiology*
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Reference Values
  • Risk Assessment
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Sex Factors

Substances

  • Creatinine